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Some of these sources may be so common that most humans are exposed to small amounts and it is difficult to apportion the exogenous and endogenous contributions Zhao et al. ROS are produced as. Types Of Free Radicals Oxidants And Their Endogenous And Exogenous Download Scientific Diagram In principle cell injury can occur due to the following factors. . The causes of cell injury are classified as exogenous or endogenous. The damage to cells caused by free radicals especially the damage to DNA may play a role in the development of cancer and other health conditions 1 2. ROS can damage lipids DNA RNA and proteins which in theory contributes to the physiology of aging. ROS have long been implicated in oxidative damage and. At high levels ROS can lead to impaired physiological function through cellular damage of DNA proteins lipids and other macromolecules which can lead to certain human pathologies including cancers neurodege...
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